Category: Miscellaneous

The EU Commission can see no excess mortality due to the COVID-19 vaccines

November 18, 2023 /

Michael Palmer, MD and Sucharit Bhakdi, MD

I only believe in statistics that I doctored myself.
Winston Churchill

1. Background

On August 29, 2023, Ivan Vilibor Sinčić, a Croatian member of the EU Parliament, posed the following simple and poignant question to the EU Commission:

Per the European Medicines Agency’s EudraVigilance system, how many people have been reported dead as a consequence (side effect) of receiving approved COVID-19 vaccines since the administration of these medical products began?

On November 6, he received the following written reply from Ms. Stella Kyriakides, the EU Commissioner for Health and Food Safety:

EudraVigilance is a database collecting suspected side effects reported by the European Economic Area’s (EEA) patients and healthcare professionals, i.e. medical events reported following the use of a medicine in the EEA.The fact that these events were observed following the use of the medicine does not mean that they were caused by it. They may have been caused by underlying medical conditions of the individual, by other medicines taken in parallel or due to other events entirely.

Scientific studies investigate potential causal links in these temporal associations and most suspected side effects are not eventually confirmed as side effects.

An unprecedent [sic] high number of people has been administered COVID-19 vaccines [1] and the number of reported suspected side effects is consequently much higher than for other medicines.

As of 30 September 2023, EudraVigilance shows 11,977 spontaneous reports of suspected side effects with reported fatal outcome for all authorised COVID-19 vaccines.

Only in very exceptional cases, deaths have been reported to be caused by the vaccine. One example is ‘thrombosis with thrombocytopenia syndrome’ with adenoviral vector COVID-19 vaccines [2] for which warnings and contraindications have been included in the product information to inform healthcare professionals and patients and reduce risk of adverse consequences.

There is no evidence that COVID-19 vaccines are causing excess mortality [3] and no safety signal for increased mortality with any of the authorised COVID-19 vaccines has been identified by EMA to date. In fact, COVID-19 vaccines have saved millions of lives.

[1] Almost 768 million vaccine doses administered in EU and EEA countries.
[2] https://www.nature.com/articles/s41541-022-00569-8
[3] https://www.icmra.info/drupal/strategicinitiatives/vaccines/safety\_statement

In this memo, we will dissect and rebut the position stated by Ms. Kyriakides on behalf of the EU Commission and of the European Medicines Agency (EMA).

2. What significance should we assign to adverse events reported in connection with COVID-19 vaccination?

Ms. Kyriakides observes that the filing of an adverse event report alone does not prove causality in this specific single case. This assertion is hardly controversial. However, should we therefore dismiss the many adverse events, including severe and fatal ones, which have been reported to EudraVigilance and to similar monitoring systems around the world?

2.1. Is the high number of reports simply due to the widespread use of the COVID-19 vaccines?

In her reply, Ms. Kyriakides suggests that the high number of adverse events reported for the COVID-19 vaccines is due simply to the large number of injected doses. This raises the question of relative risk: is a single dose of a COVID-19 vaccine equally likely, less likely, or more likely to result in an adverse event report than a dose of a conventional vaccine?

Montano [1] has addressed this question by comparing the four major COVID-19 vaccines to all influenza vaccines used within the EU and the US, using data from both the American vaccine adverse events reporting system (VAERS) and the EU’s very own EudraVigilance database. For the latter, his findings are summarized in Figure 1, which gives the risks of death, life-threatening reactions, and hospital admission associated being reported after each dose of a COVID vaccine, relative to the average of all influenza vaccines. Evidently, the risk is tens of times higher with each of the COVID-19 vaccines, across all three degrees of event severity. According to VAERS, the risk is even hundreds of times higher—it would literally be off the charts in this figure.

Montano’s data were published in early 2022. EMA’s own experts, and Ms. Kyriakides herself, should of course have already been on top of this highly concerning development, rather than waiting for an academic researcher to point it out to them. Their continued pretence that all is well even after this analysis had been put on the record is entirely indefensible.

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Figure 1: Relative risks, per dose, of reports of death, life-threatening reactions, and hospital admission associated with each of the four major gene-based COVID-19 vaccines, compared to all influenza vaccines combined. Data from the EU’s EudraVigilance database, for the time period of December 2020 to October 2021 and according to Table 1 in Montano [1].

2.2. Passive adverse event reporting systems are prone to under-reporting

In her reply, Ms. Kyriakides contrasts the number of 11,977 reported fatalities with that of 768 million administered doses. This comparison might suggest that the absolute risk of death after a COVID-19 injection is indeed low, regardless of the relative risk compared to other, conventional vaccines.

We should first note that the total stated by Ms. Kyriakides is suspicious. Independent researcher Brian Shilhavy, who has closely monitored both VAERS and Eurdavigilance, retrieved 46,999 reports of fatal cases from the latter system as of August 2022 [2]. With VAERS, similar discrepancies emerge between the numbers stated by officials and by independent analysts [3].

More fundamentally, however, we must observe that both VAERS and EudraVigilance are passive systems, i.e. they merely collect reports filed by healthcare practitioners or patients on their own initiative. It is generally understood that such systems are subject to significant under-reporting. A review on the subject, which surveyed 37 original studies, found that in most of these more than 90% of all adverse drug reactions went unreported (see Figure 2). Lazarus et al. [4], who looked at VAERS specifically, concluded that less than 1% of vaccine adverse events that occur end up being reported to this system. This estimate was made already in 2010, but we can see no reason to believe that the situation has substantially improved with respect to the COVID-19 vaccines.

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Figure 2: Histogram of drug adverse event under-reporting rates across 37 original studies. Figure adapted from Hazell and Shakir [5].

2.3. Evidence of under-reporting of COVID-19 vaccine adverse events in EudraVigilance

For EudraVigilance, we can derive clear indications of significant under-reporting by simply comparing the reporting rates between the system’s member countries. This has been done in Figure 3. The highest ratio of adverse event reports per 1000 vaccine injections is shown for Iceland. However, in this case the vaccination count extends only to the end of March 2022, while the number of adverse events was counted on September 9, which will of course inflate their incidence. Similar caveats apply to Slovakia and Latvia. But no such distortion exists with the Netherlands, where the two dates differ by only one week. We can therefore use the Dutch reporting rate as a reference.

In Spain, the reporting rate is only one eighth of the Dutch. Therefore, even if we very optimistically assumed that in Holland every single adverse event is reported, then we still would have to conclude that only one in eight adverse events gets reported in Spain. Also note the rather low reporting rates in the most populous EU countries—aside from Spain, these are Germany, France, and Italy. Overall, the reporting rate from all listed countries, weighted for population and excluding the Netherlands, is 21% of the Dutch reporting rate. Even though this figure most likely still overestimates the true reporting rate, it indicates that the problem of under-reporting remains significant and serious.

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Figure 3: Adverse events reported per 1000 injections of COVID-19 vaccines for 18 EU member countries. Vaccination rates from [6]; numbers of adverse event reports from [7] and as of September 9, 2022. Vaccination rates are from within one week before or after that reference date, with the exception of Iceland, Slovakia, and Latvia, for which the latest vaccination rates available were from up to 6 months earlier. This will tend to inflate the ratio of adverse event reports to vaccinations.

2.4. Estimates of COVID-19 vaccine fatalities from a representative survey in the United States

The above conclusions align with those arrived at by economist Mark Skidmore, based on a representative survey of COVID-19 vaccine decisions and experiences in the United States [8]. From his analysis of these data, Skidmore infers that approximately 278,000 vaccine-related fatalities had occurred already by the end of 2021, and within the United States alone. If a similar survey were conducted now, this number would likely be considerably higher. There is no reason to believe that the situation looks any rosier within the European Union.

2.5. Spikes in all-cause mortality correlate with COVID-19 vaccination

Multiple independent investigators have examined the relationship between trends in all-cause mortality and the roll-out of COVID-19 vaccines. They find a striking correlation of spikes in mortality with the timing of vaccination campaigns [9,10]. Furthermore, a clear correlation can be detected between national trends in mortality and rates of vaccine uptake [11]. As but one example, Figure 4 shows how each spike in vaccine injections coincides with one in all-cause mortality; and from the relative magnitude of those coinciding peaks, it appears that each successive dose is more effective in this regard. Also note that in 2020 mortality did not exceed that in 2019—obviously, the virus itself was not particularly deadly. This was of course already known before the vaccinations started, and it had been properly and formally published by leading epidemiologist John Ioannidis already in 2020, in the Bulletin of the WHO [12]. Such findings make it clear that the alleged “emergency,” which was invoked by the authorities to justify the extraordinary risky vaccination program, never existed.

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Figure 4: Time correlation of spikes in all-cause mortality with COVID-19 vaccination campaigns in Australia. Figure adapted from Rancourt et al. [9].

2.6. On the proper use of passive adverse event reporting systems

Hazell and Shakir [5] draw the obvious and appropriate conclusions from the widespread and significant under-reporting bias of passive reporting systems, explaining what such systems can or cannot be used for:

The main function of the SRS [spontaneous, i.e. passive reporting system] is early detection of signals of new, rare or serious ADRs [adverse drug reactions]. These reactions may not have been detected by the relatively small numbers of patients included in premarketing clinical trials or by larger postmarketing surveillance studies. The SRS has the advantage of covering a large number of patients, i.e. the entire population, and a wide range of drugs. It is therefore a relatively cost-effective method of monitoring drug safety.The SRS does, however, have a number of limitations. Data from the SRS, when taken alone, do not accurately quantify the risk associated with a drug.

In other words, EudraVigilance and similar institutions simply serve as early warning systems. While it must be understood that the magnitude of any signal from such a system will likely be underestimated, it can nevertheless be expected to highlight emerging problems quickly. Of course, this is exactly what occurred with the COVID-19 vaccines. EMA and the EU Commission, as the stewards of the EudraVigilance system, must therefore answer the following question: what did they do in response to this early and glaringly obvious danger signal? The only answer one can find on the public record is this: they did their best to bury it.

3. Is there really no proof of a causal connection to death and disease?

Ms. Kyriakides asserts that “only in very exceptional cases, deaths have been reported to be caused by the vaccine.” She cites a single relevant study and suggests that the problem affects only or mostly the adenoviral vaccines, and that the public is already being appropriately informed and cautioned.

In fact, and in contrast to the impression conveyed by Ms. Kyriakides, the number of published reports on fatal cases is substantial, in spite of widespread censorship.1 Ms. Kyriakides may find it instructive to peruse references [18–40], most of which attribute the death of one or more patients directly to vaccination, although some of the reports pertain to the deaths by COVID-19 of vaccinated patients, thus highlighting the futility of this “safe and effective” intervention. And as with the passive monitoring systems discussed above, we must assume that the number of published cases is only the tip of the iceberg. This is well illustrated by the work of Arne Burkhardt and Walter Lang, two emeritus professors of pathology, who have examined the autopsy materials of numerous patients that had died soon after receiving a COVID-19 vaccine. As stated in our previous summary of their work [41],2 these cases had initially been autopsied by other physicians, who had certified the cause of death as “natural” or “unknown.” Burkhardt and Lang became involved only because the bereaved families doubted these verdicts and sought a second opinion. It is remarkable, therefore, that Burkhardt and Lang found not just a few but the majority of these deaths to have been due to vaccination, with a high or even very high degree of probability.

We also must remind Ms. Kyriakides that the EMA, and by extension the EU Commission, were warned early on about the dangers of the gene-based COVID-19 vaccinations. In an urgent open letter to the EMA [43], a large number of physicians and medical scientists (also including the authors of this document) spelled out the risks and the likely key mechanism of acute vascular disease, many cases of which were already being reported very shortly after the vaccines had been approved for emergency use. This damage mechanism has since been fully substantiated by the histopathological studies carried out by Burkhardt, Lang, and others; and it has been found to affect not only the blood vessels but also organ-specific cells and tissues everywhere in the body. In one particularly important study, pathologist Michael Mörz has provided definitive evidence of a direct link between vaccine injection and destructive inflammation of the brain and the heart [44]. The patient in question, having experienced progressive deterioration after each injection, finally succumbed to the third one.

4. Conclusion

The evidence of harm and death due to the COVID-19 vaccines, which emerged within mere days of their roll-out, has since become utterly obvious and devastating. EMA’s failure to “detect a safety signal” constitutes a safety signal all unto itself. This signal has been detected by the public, which is turning its back on the vaccines and, by extension, on Ms. Kyriakides and Europe’s entire criminally negligent administration.

The toxicity of the gene-based vaccines was understood and predicted even before they were introduced, and the anticipated central mechanism of such toxicity has since been abundantly confirmed. This is discussed in more detail in our recent book “mRNA Vaccine Toxicity” [45], which can be downloaded and read for free. The book spells out that the grave harm observed with the COVID-19 vaccines must be expected with future gene-based vaccines against other infectious diseases also. We hope that you will spread this message and share it with your friends and family.

Notes

  1. Multiple studies that highlighted risks and dangers of COVID-19 vaccination were “retracted” after initial acceptance and publication [13–17], without any substantial or comprehensible justification. The number of studies which never even saw the light of day to begin with is very likely much higher.(go back)
  2. Prof. Burkhardt, though not a co-author, reviewed and approved our account of his work. He had co-authored a memorandum with Prof. Bhakdi at an earlier time, which pertained to a smaller number of patients but arrived at essentially the same conclusions [42]. Prof. Burkhardt died in 2023.(go back)

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Alternate mechanisms of mRNA vaccine toxicity: which one is the main culprit?

April 29, 2023 /

Michael Palmer, MD

This paper summarizes the mode of action of mRNA vaccines, as well as three potential pathogenetic mechanisms that may account for the toxicity observed with the mRNA vaccines against COVID-19, namely: chemical toxicity of lipid nanoparticles, direct toxicity of the spike protein, whose expression is induced by the vaccines, and the destructive effects of the immune response to the spike protein. The case is made that of these mechanism the third is likely the most important one. If this conclusion is correct, then essentially the same level of toxicity must be expected with future mRNA vaccines against any other pathogenic microbes.

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Did Pfizer Perform Adequate Safety Testing for its Covid-19 mRNA Vaccine in Preclinical Studies? Evidence of Scientific and Regulatory Fraud

June 7, 2022 /

by Sasha Latypova

The rushed “warp speed” development and approval of completely novel Covid-19 mRNA and DNA vaccines pushed on the people of the world has resulted until today in millions of reported injuries and thousands of deaths according to public health databases such as VAERS (US), EudraVigilance (EU), Yellow Card (UK) and others. This article reviews some of the publicly available documents on Pfizer’s non-clinical development program and points out its deficiencies, omissions and gaps, which were very obvious, yet were never questioned by the regulators or other health authorities. The cursory nature of the entire preclinical program can be summed up as “we did not find any safety signals because we did not look for them.” The omission of safety studies which are considered standard or even mandatory, and the scientific dishonesty in those studies which were performed are so obvious and glaring that they cannot be attributed to the incompetence of the manufacturers and regulators. Rather, the question of wilful negligence must be raised.

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Could the current monkeypox outbreak be natural?

June 4, 2022 /

(First published on doctors4covidethics.org)

Hot on the heels of the man-made COVID-19 “pandemic”, the world is witnessing another suspicious outbreak—this time of monkeypox, which is endemic in Central and West Africa but has so far only sporadically appeared outside this area. In contrast, the current outbreak affects more than twenty countries outside Africa. I here examine whether it is plausible that this could have happened naturally.

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The ban of DDT did not cause millions to die from malaria

April 16, 2022 /

On various blogs and websites dedicated to science and politics, usually of conservative persuasion, it is often alleged that the ban of the insecticide DDT, motivated by concerns about its damaging effects on the environment, has caused tens of millions in avoidable malaria fatalities over the last couple of decades. This position is untenable in light of the following scientific and historic facts:

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Storm tides and coastal protection on the German North Sea shore

April 11, 2022 /

The North Sea is the shelf sea between Great Britain in the West and continental Europe in the East and South. It has strong tidal movements, and is prone to storm surges that occur when north-westerly winds whip the sea against the continental coast. The most severe surges tend to arise when storms combine with spring tides, during which the sun, moon and earth are all lined up to maximize the gravitational pull on the water. The coastal people have long fought and laboured to protect their lives and their land from the elements. Their history should be of interest to anyone worrying about the best way to adapt to “climate change” or “extreme weather”.

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Elementary, my dear Watson: why mRNA vaccines are a very bad idea

April 11, 2022 /

Michael Palmer, MD and Sucharit Bhakdi, MD

doctors4covidethics.org

Pfizer’s and Moderna’s mRNA-based COVID-19 vaccines have caused injury and death on an unprecedented scale. This short article explains from first principles why adverse events must be expected not just after the first injection of such a vaccine but after each booster shot as well. The argument is not limited to SARS-CoV-2 or its spike protein but applies generally to any non-self antigen introduced in the form of mRNA. Accordingly, not only must the COVID mRNA vaccines be stopped, but mRNA vaccines should never be used again, regardless of the infectious agent in question.

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